For a full list see: PubMed or Google scholar

2024

H3K4me1 facilitates promoter-enhancer interactions and gene activation during embryonic stem cell differentiation. Kubo N, Chen PB, Hu R, Ye Z, Sasaki H, Ren B. Mol Cell., 2024 Mar 15:S1097-2765(24)00171-0.

RUNX1 C-terminal mutations impair blood cell differentiation by perturbing specific enhancer-promoter networks. Jayne ND, Liang Z, Lim DH, Chen PB, Diaz C, Arimoto KI, Xia L, Liu M, Ren B, Fu XD, Zhang DE. Blood Adv., 2024 Mar 21:bloodadvances.2023011484.

2022

Systematic discovery and functional dissection of enhancers needed for cancer cell fitness and proliferation. Chen PB, Fiaux PC, Li B, Zhang K, Kubo N, Jiang S, Hu R, Rooholfada E, Wu S, Wang M, Wang W, McVicker G, Mischel PS, Ren B. Cell Rep., 2022 Nov 8;41(6):111630.

2021

CRISPR-SE: A brute force search engine for CRISPR design. Li B, Chen PB, Diao Y. NAR Genom Bioinform. 2021 Feb 23:3(1):lqab013.

2020

Directed remodeling of the mouse gut microbiome inhibits the development of atherosclerosis. Chen PB, Black AS, Sobel AL, Zhao Y, Mukherjee P, Molparia B, Moore NE, Muench G, Wu J, Chen W, Pinto A, Maryanoff BE, Saghatelian A, Soroosh P, Torkamani A, Leman LJ, Ghadiri MR. Nat Biotechnol. 2020 Nov; 38(11): 1288-1297.

Discovering functional sequences with RELICS, an analysis method for tiling CRISPR screens. Fiaux PC, Chen HV, Chen PB, Chen AR, McVicker G. PLOS Comput Biol. 2020 Sep 16; 16 (9):e1008194.

Patent

Chemotherapeutic remodeling of gut microbiome (2018). Ghadiri MR, Leman LJ, Chen PB, Zhao Y, Torkamani A, Black AS